Anti-IL-1 Receptor Antagonist Protein-Tag antibody [R01-6J5] (STJA0034467)

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STJA0034467
£133.50 - £281.50
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Host: Rabbit
Applications: WB/IHC-F/IHC-P/ICC/IF/IP
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-IL-1 Receptor Antagonist Protein-Tag for use in WB, IHC-F, IHC-P, ICC, IF and IP in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R01-6J5
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
IF 1:50-1:200
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: IL1RN
Gene ID: 3557
Uniprot ID: IL1RA_HUMAN
Immunogen: A synthetic peptide of human IL1RA
Tissue Specificity The intracellular form of IL1RN is predominantly expressed in epithelial cells.
Function Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
Protein Name Interleukin-1 Receptor Antagonist Protein
Il-1rn
Il-1ra
Irap
Icil-1ra
Il1 Inhibitor
Anakinra
Database Links Reactome: R-HSA-6783783
Reactome: R-HSA-9020702
Cellular Localisation Isoform 1: Secreted
Isoform 2: Cytoplasm
Isoform 3: Cytoplasm
Isoform 4: Cytoplasm
Alternative Antibody Names Anti-Interleukin-1 Receptor Antagonist Protein antibody
Anti-Il-1rn antibody
Anti-Il-1ra antibody
Anti-Irap antibody
Anti-Icil-1ra antibody
Anti-Il1 Inhibitor antibody
Anti-Anakinra antibody
Anti-IL1RN antibody
Anti-IL1F3 antibody
Anti-IL1RA antibody

Information sourced from Uniprot.org

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