Anti-IL-1 beta antibody [SM0422] (STJA0010422)

SKU:
STJA0010422
€213.13 - €291.88
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-IL-1 beta is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality : Monoclonal
Clone ID : SM0422
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: PBS with 0.15% ProClin300, 100 Mu g/mL BSA and 50% glycerol.
Purification: Affinity purification
Dilution Range: IHC/IF (H, M, R) 1:300-1:600
Storage Instruction: Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.
Gene Symbol: Il1b
Uniprot ID: IL1B_RAT
Immunogen: Recombinant protein corresponding to Rat IL-1 beta
Protein Name Interleukin-1 Beta
Il-1 Beta
Cellular Localisation Cytoplasm
Cytosol
Secreted
Lysosome
Extracellular Exosome
The Precursor Is Cytosolic
In Response To Inflammasome-Activating Signals
Such As Atp For Nlrp3 Inflammasome Or Bacterial Flagellin For Nlrc4 Inflammasome
Cleaved And Secreted
Mature Form Is Secreted And Released In The Extracellular Milieu By Passing Through The Gasdermin-D (Gsdmd) Pore
In Contrast
The Precursor Form Is Not Released
Due To The Presence Of An Acidic Region That Is Proteolytically Removed By Casp1 During Maturation
The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10
Alternative Antibody Names Anti-Interleukin-1 Beta antibody
Anti-Il-1 Beta antibody
Anti-Il1b antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ73078 Anti-IL-1 beta antibody (Internal) (STJ73078) Goat Polyclonal Human Pep-ELISA/WB
STJA0010462 Anti-IL-1 beta antibody [SM0462] (STJA0010462) Mouse Monoclonal Human/Mouse WB
STJA0010498 Anti-IL-1 beta antibody [SM0498] (STJA0010498) Mouse Monoclonal Mouse WB
STJAP00585 Porcine IL-1 Beta (IL-1 Beta) Antibody Pair (STJAP00585) Mouse/Goat Porcine ELISA
STJAP00006 Mouse IL-1 Beta (Interleukin-1 Beta) Antibody Pair (STJAP00006) Rat/Goat Monoclonal/Polyclonal Mouse ELISA

Related Products

!