| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IGHMBP2 |
| Gene ID: | 3508 |
| Uniprot ID: | SMBP2_HUMAN |
| Immunogen Region: | 540-720 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human IGHMBP2 (NP_002171.2). |
| Immunogen Sequence: | PYNLQVDLLRQSLVHRHPEL EIKSVDGFQGREKEAVILSF VRSNRKGEVGFLAEDRRINV AVTRARRHVAVICDSRTVNN HAFLKTLVEYFTQHGEVRTA FEYLDDIVPENYSHENSQGS SHAATKPQGPATSTRTGSQR QEGGQEAAAPARQGRKKPAG KSLASEAPSQPSLNGGSPEG V |
| Tissue Specificity | Expressed in all tissues examined. Expressed in the developing and adult human brain, with highest expression in the cerebellum. Moderately expressed in fibroblasts. |
| Function | 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr. |
| Protein Name | Dna-Binding Protein Smubp-2Atp-Dependent Helicase Ighmbp2Glial Factor 1Gf-1Immunoglobulin Mu-Binding Protein 2 |
| Cellular Localisation | NucleusCytoplasmCell ProjectionAxon |
| Alternative Antibody Names | Anti-Dna-Binding Protein Smubp-2 antibodyAnti-Atp-Dependent Helicase Ighmbp2 antibodyAnti-Glial Factor 1 antibodyAnti-Gf-1 antibodyAnti-Immunoglobulin Mu-Binding Protein 2 antibodyAnti-IGHMBP2 antibodyAnti-SMBP2 antibodyAnti-SMUBP2 antibody |
Information sourced from Uniprot.org