• Immunohistochemistry analysis of IGHMBP2 in paraffin-embedded mouse liver using IGHMBP2 Rabbit polyclonal antibody (STJ118494) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of IGHMBP2 in paraffin-embedded human mammary cancer using IGHMBP2 Rabbit polyclonal antibody (STJ118494) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of IGHMBP2 in paraffin-embedded human lung cancer using IGHMBP2 Rabbit polyclonal antibody (STJ118494) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of IGHMBP2 in paraffin-embedded rat brain using IGHMBP2 Rabbit polyclonal antibody (STJ118494) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of various lysates using IGHMBP2 Rabbit polyclonal antibody (STJ118494) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-IGHMBP2 antibody (540-720) (STJ118494)

SKU:
STJ118494

£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IHC-P:1:50-1:100
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IGHMBP2
Gene ID: 3508
Uniprot ID: SMBP2_HUMAN
Immunogen Region: 540-720
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 540-720 of human IGHMBP2 (NP_002171.2).
Immunogen Sequence: PYNLQVDLLRQSLVHRHPEL EIKSVDGFQGREKEAVILSF VRSNRKGEVGFLAEDRRINV AVTRARRHVAVICDSRTVNN HAFLKTLVEYFTQHGEVRTA FEYLDDIVPENYSHENSQGS SHAATKPQGPATSTRTGSQR QEGGQEAAAPARQGRKKPAG KSLASEAPSQPSLNGGSPEG V
Tissue Specificity Expressed in all tissues examined. Expressed in the developing and adult human brain, with highest expression in the cerebellum. Moderately expressed in fibroblasts.
Function 5' to 3' helicase that unwinds RNA and DNA duplexes in an ATP-dependent reaction. Specific to 5'-phosphorylated single-stranded guanine-rich sequences. May play a role in RNA metabolism, ribosome biogenesis or initiation of translation. May play a role in regulation of transcription. Interacts with tRNA-Tyr.
Protein Name Dna-Binding Protein Smubp-2
Atp-Dependent Helicase Ighmbp2
Glial Factor 1
Gf-1
Immunoglobulin Mu-Binding Protein 2
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Axon
Alternative Antibody Names Anti-Dna-Binding Protein Smubp-2 antibody
Anti-Atp-Dependent Helicase Ighmbp2 antibody
Anti-Glial Factor 1 antibody
Anti-Gf-1 antibody
Anti-Immunoglobulin Mu-Binding Protein 2 antibody
Anti-IGHMBP2 antibody
Anti-SMBP2 antibody
Anti-SMUBP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance