Anti-Ighm antibody [RMM-1] {AF488} (STJA0002069)

SKU:
STJA0002069

Current Stock:
Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Immunoglobulin heavy constant mu is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: RMM-1
Conjugation: AF488
Isotype: IgG2ak
Formulation: PBS with 0.05% Proclin300, 1% BSA
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: IghmUniprot ID=IGHM_MOUSE"
Tissue Specificity Mu' chain is expressed in bone marrow.
Post Translational Modifications Cleaved by a non-enzymatic process after Asn-96, yielding a glycosylated protein of 55 kDa. The process is induced by other proteins, and requires neutral or alkaline pH.
Function IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions.
Protein Name Immunoglobulin Heavy Constant Mu Cleaved Into - Mu' Chain
55 Kda Mu' Chain
Cellular Localisation Isoform 1: Secreted
During Differentiation
B-Lymphocytes Switch From Expression Of Membrane-Bound Igm To Secretion Of Igm
Isoform 2: Cell Membrane
Single-Pass Membrane Protein
Alternative Antibody Names Anti-Immunoglobulin Heavy Constant Mu Cleaved Into - Mu' Chain antibody
Anti-55 Kda Mu' Chain antibody
Anti-Ighm antibody
Anti-Igh-6 antibody

Information sourced from Uniprot.org

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