| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IGFBP7 |
| Gene ID: | 3490 |
| Uniprot ID: | IBP7_HUMAN |
| Immunogen Region: | 27-282 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-282 of human IGFBP7 (NP_001544.1). |
| Immunogen Sequence: | SSSDTCGPCEPASCPPLPPL GCLLGETRDACGCCPMCARG EGEPCGGGGAGRGYCAPGME CVKSRKRRKGKAGAAAGGPG VSGVCVCKSRYPVCGSDGTT YPSGCQLRAASQRAESRGEK AITQVSKGTCEQGPSIVTPP KDIWNVTGAQVYLSCEVIGI PTPVLIWNKVKRGHYGVQRT ELLPGDRDNLAIQTRGGPEK HEVTGWVLVSPLSKEDAGEY ECHASNSQGQASASAKITV |
| Post Translational Modifications | N-glycosylated. |
| Function | Binds IGF1 and IGF2 with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. Acts as a ligand for CD93 to play a role in angiogenesis. |
| Protein Name | Insulin-Like Growth Factor-Binding Protein 7Ibp-7Igf-Binding Protein 7Igfbp-7Igfbp-Rp1Mac25 ProteinPgi2-Stimulating FactorProstacyclin-Stimulating FactorTumor-Derived Adhesion FactorTaf |
| Database Links | Reactome: R-HSA-2559582Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Insulin-Like Growth Factor-Binding Protein 7 antibodyAnti-Ibp-7 antibodyAnti-Igf-Binding Protein 7 antibodyAnti-Igfbp-7 antibodyAnti-Igfbp-Rp1 antibodyAnti-Mac25 Protein antibodyAnti-Pgi2-Stimulating Factor antibodyAnti-Prostacyclin-Stimulating Factor antibodyAnti-Tumor-Derived Adhesion Factor antibodyAnti-Taf antibodyAnti-IGFBP7 antibodyAnti-MAC25 antibodyAnti-PSF antibody |
Information sourced from Uniprot.org