• STJ71555 (0. 5µg/ml) staining of Human Adrenal Gland lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • HEK293 overexpressing IGFBP6 (RC204060) and probed with STJ71555 (mock transfection in first lane) , tested by Origene.

Anti-IGFBP6 antibody (Internal) (STJ71555)

SKU:
STJ71555-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-IGFBP6 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx. 25kDa band observed in Human Adrenal Gland lysates (calculated MW of 25.3kDa according to NP_002169.1). In transfected HEK293 transiently expressing IGFBP6 a band of approx. 29
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: IGFBP6
Gene ID: 3489
Uniprot ID: IBP6_HUMAN
Immunogen Region: Internal
Accession Number: NP_002169.1
Immunogen Sequence: RPQDVNRRDQQRNP
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration.
Protein Name Insulin-Like Growth Factor-Binding Protein 6
Ibp-6
Igf-Binding Protein 6
Igfbp-6
Database Links Reactome: R-HSA-381426
Cellular Localisation Secreted
Alternative Antibody Names Anti-Insulin-Like Growth Factor-Binding Protein 6 antibody
Anti-Ibp-6 antibody
Anti-Igf-Binding Protein 6 antibody
Anti-Igfbp-6 antibody
Anti-IGFBP6 antibody
Anti-IBP6 antibody

Information sourced from Uniprot.org

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