Anti-IFT88 antibody (534-833 aa) [S4895RM] (STJ11104895)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Intraflagellar Transport Protein 88 Homolog (534-833 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4895RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IFT88 |
| Gene ID | 8100 |
| Uniprot ID | IFT88_HUMAN |
| Immunogen Region | 534-833 aa |
| Immunogen Sequence | GLTYEKLNRLDEALDCFLKL HAILRNSAEVLYQIANIYEL MENPSQAIEWLMQVVSVIPT DPQVLSKLGELYDREGDKSQ AFQYYYESYRYFPCNIEVIE WLGAYYIDTQFWEKAIQYFE RASLIQPTQVKWQLMVASCF RRSGNYQKALDTYKDTHRKF PENVECLRFLVRLCTDLGLK DAQEYARKLKRLEKMKEIRE QRIKSGRDGSGGSRGKREGS ASGDSGQNYSASSKGERLS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 534-833 of human IFT88. (NP_783195.2). |
Additional Info
| Tissue Specificity | Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas. |
| Function | Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment. |
| Protein Name | Intraflagellar Transport Protein 88 HomologRecessive Polycystic Kidney Disease Protein Tg737 HomologTetratricopeptide Repeat Protein 10Tpr Repeat Protein 10 |
| Database Links | Reactome: R-HSA-5610787Reactome: R-HSA-5620924Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9646399 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCell ProjectionCiliumCilium Basal BodyFlagellumColocalizes With Entr1 And Gamma-Tubulin At The Basal Body Of Primary CiliaColocalizes With Entr1 And Pericentrin At The CentrosomeIn Sperm CellsLocalizes To The ManchetteHead-Tail Coupling Apparatus And Flagellum |
| Alternative Antibody Names | Anti-Intraflagellar Transport Protein 88 Homolog antibodyAnti-Recessive Polycystic Kidney Disease Protein Tg737 Homolog antibodyAnti-Tetratricopeptide Repeat Protein 10 antibodyAnti-Tpr Repeat Protein 10 antibodyAnti-IFT88 antibodyAnti-TG737 antibodyAnti-TTC10 antibody |
Information sourced from Uniprot.org