Anti-IFT88 antibody (534-833 aa) [S4895RM] (STJ11104895)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11104895
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General Information

Short DescriptionRabbit monoclonal Intraflagellar Transport Protein 88 Homolog (534-833 aa) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS4895RM
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolIFT88
Gene ID8100
Uniprot IDIFT88_HUMAN
Immunogen Region534-833 aa
Immunogen SequenceGLTYEKLNRLDEALDCFLKL HAILRNSAEVLYQIANIYEL MENPSQAIEWLMQVVSVIPT DPQVLSKLGELYDREGDKSQ AFQYYYESYRYFPCNIEVIE WLGAYYIDTQFWEKAIQYFE RASLIQPTQVKWQLMVASCF RRSGNYQKALDTYKDTHRKF PENVECLRFLVRLCTDLGLK DAQEYARKLKRLEKMKEIRE QRIKSGRDGSGGSRGKREGS ASGDSGQNYSASSKGERLS
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 534-833 of human IFT88. (NP_783195.2).

Additional Info

Tissue Specificity Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
Function Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.
Protein Name Intraflagellar Transport Protein 88 Homolog
Recessive Polycystic Kidney Disease Protein Tg737 Homolog
Tetratricopeptide Repeat Protein 10
Tpr Repeat Protein 10
Database Links Reactome: R-HSA-5610787
Reactome: R-HSA-5620924
Reactome: R-HSA-9613829
Reactome: R-HSA-9615710
Reactome: R-HSA-9646399
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Cell Projection
Cilium
Cilium Basal Body
Flagellum
Colocalizes With Entr1 And Gamma-Tubulin At The Basal Body Of Primary Cilia
Colocalizes With Entr1 And Pericentrin At The Centrosome
In Sperm Cells
Localizes To The Manchette
Head-Tail Coupling Apparatus And Flagellum
Alternative Antibody Names Anti-Intraflagellar Transport Protein 88 Homolog antibody
Anti-Recessive Polycystic Kidney Disease Protein Tg737 Homolog antibody
Anti-Tetratricopeptide Repeat Protein 10 antibody
Anti-Tpr Repeat Protein 10 antibody
Anti-IFT88 antibody
Anti-TG737 antibody
Anti-TTC10 antibody

Information sourced from Uniprot.org

Citations

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