Host: |
Rabbit |
Applications: |
ELISA/IHC/IP/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ICMT (230-284) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.55-0.75 µg/µl |
Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:100 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
ICMT |
Gene ID: |
23463 |
Uniprot ID: |
ICMT_HUMAN |
Immunogen Region: |
230-284 |
Immunogen: |
Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase. |
Tissue Specificity | Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons. |
Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. |
Protein Name | Protein-S-Isoprenylcysteine O-MethyltransferaseIsoprenylcysteine CarboxylmethyltransferasePrenylated Protein Carboxyl MethyltransferasePpmtPrenylcysteine Carboxyl MethyltransferasePccmt |
Database Links | Reactome: R-HSA-163841Reactome: R-HSA-9648002 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Protein-S-Isoprenylcysteine O-Methyltransferase antibodyAnti-Isoprenylcysteine Carboxylmethyltransferase antibodyAnti-Prenylated Protein Carboxyl Methyltransferase antibodyAnti-Ppmt antibodyAnti-Prenylcysteine Carboxyl Methyltransferase antibodyAnti-Pccmt antibodyAnti-ICMT antibodyAnti-PCCMT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance