| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-ICMT (230-284) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.75 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | ICMT |
| Gene ID: | 23463 |
| Uniprot ID: | ICMT_HUMAN |
| Immunogen Region: | 230-284 |
| Immunogen: | Synthetic peptide taken within amino acid region 230-284 on human Protein-S-isoprenylcysteine O-methyltransferase. |
| Tissue Specificity | Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons. |
| Function | Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues. |
| Protein Name | Protein-S-Isoprenylcysteine O-MethyltransferaseIsoprenylcysteine CarboxylmethyltransferasePrenylated Protein Carboxyl MethyltransferasePpmtPrenylcysteine Carboxyl MethyltransferasePccmt |
| Database Links | Reactome: R-HSA-163841Reactome: R-HSA-9648002 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein-S-Isoprenylcysteine O-Methyltransferase antibodyAnti-Isoprenylcysteine Carboxylmethyltransferase antibodyAnti-Prenylated Protein Carboxyl Methyltransferase antibodyAnti-Ppmt antibodyAnti-Prenylcysteine Carboxyl Methyltransferase antibodyAnti-Pccmt antibodyAnti-ICMT antibodyAnti-PCCMT antibody |
Information sourced from Uniprot.org