Anti-ICE2 antibody (474-524) (STJA0006645)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human NARG2 AA range: 474-524
General Information
| Short Description | Rabbit polyclonal anti-Little elongation complex subunit 2 (474-524) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ICE2 |
| Gene ID | 79664 |
| Uniprot ID | ICE2_HUMAN |
| Immunogen | Synthesized peptide derived from human NARG2 AA range: 474-524 |
| Immunogen Region | 474-524 |
| Specificity | This antibody detects endogenous levels of human NARG2 |
Additional Info
| Function | Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. |
| Protein Name | Little Elongation Complex Subunit 2Interactor Of Little Elongator Complex Ell Subunit 2Nmda Receptor-Regulated Protein 2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusColocalizes With Coil In Subnuclear Cajal And Histone Locus BodiesTranslocates In The Lec Complex To Cajal And Histone Locus Bodies At Snrna Genes In A Ice1-Dependent MannerAssociates To Transcriptionally Active Chromatin At Snrna Genes |
| Alternative Antibody Names | Anti-Little Elongation Complex Subunit 2 antibodyAnti-Interactor Of Little Elongator Complex Ell Subunit 2 antibodyAnti-Nmda Receptor-Regulated Protein 2 antibodyAnti-ICE2 antibodyAnti-BRCC1 antibodyAnti-NARG2 antibodyAnti-UNQ3101 antibodyAnti-PRO10100 antibody |
Information sourced from Uniprot.org