Anti-ICAM3 antibody [R08-0D3] (STJA0035231)

SKU:
STJA0035231
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-ICAM3 for use in WB, IHC-P and IP in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/IP
Host:Rabbit
Reactivity:Human/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R08-0D3
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.3 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IP 1:20
Formulation:50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:ICAM3
Gene ID:3385
Uniprot ID:ICAM3_HUMAN
Immunogen:A synthetic peptide of human ICAM3
Tissue Specificity Leukocytes.
Post Translational Modifications Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated.glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
Protein Name Intercellular Adhesion Molecule 3
Icam-3
Cdw50
Icam-R
Cd Antigen Cd50
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-5621575
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 3 antibody
Anti-Icam-3 antibody
Anti-Cdw50 antibody
Anti-Icam-R antibody
Anti-Cd Antigen Cd50 antibody
Anti-ICAM3 antibody

Information sourced from Uniprot.org