| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-ICAM2/CD102 (1-240) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4089RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Icam2 |
| Gene ID: |
15896 |
| Uniprot ID: |
ICAM2_MOUSE |
| Immunogen Region: |
1-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of mouse ICAM2/CD102 (P35330). |
| Immunogen Sequence: |
MSSFACWSLSLLILFYSPGS GEKAFEVYIWSEKQIVEATE SWKINCSTNCAAPDMGGLET PTNKIMLEEHPQGKWKQFLV SNVSKDTVFFCHFTCSGKQH SESLNIRVYQPPAQVTLKLQ PPRVFVGEDFTIECTVSPVQ PLERLTLSLLRGRETLKNQT FGGAETVPQEATATFNSTAL KKDGLNFSCQAELDLRPHGG YIIRSISEYQILEVYEPMQD NQMVIIIVVVSILLFLFVT |
| Tissue Specificity | Expressed in endothelial cells and leukocytes. High levels found in lung. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
| Protein Name | Intercellular Adhesion Molecule 2Icam-2Lymphocyte Function-Associated Ag-1 Counter-ReceptorCd Antigen Cd102 |
| Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083Reactome: -MMU-5621575 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 2 antibodyAnti-Icam-2 antibodyAnti-Lymphocyte Function-Associated Ag-1 Counter-Receptor antibodyAnti-Cd Antigen Cd102 antibodyAnti-Icam2 antibodyAnti-Icam-2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
