Anti-ICAM1 antibody [PT0133R] (STJA0039737)

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STJA0039737
€187.50 - €675.00
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Host: Rabbit
Applications: WB/IHC/IF/IP/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Intercellular Adhesion Molecule 1 for use in WB, IHC, IF, IP and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : PT0133R
Conjugation: Unconjugated
Isotype: IgGk
Formulation: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification: Protein A
Dilution Range: IHC 1:100-200
WB 1:1000-5000
IF 1:200-1000
ELISA 1:5000-20000
IP 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ICAM1
Gene ID: 3383
Uniprot ID: ICAM1_HUMAN
Specificity: Endogenous
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Major Group Rhinovirus Receptor
Cd Antigen Cd54
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-877300
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 1 antibody
Anti-Icam-1 antibody
Anti-Major Group Rhinovirus Receptor antibody
Anti-Cd Antigen Cd54 antibody
Anti-ICAM1 antibody

Information sourced from Uniprot.org

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