Anti-ICAM1 antibody [PT0133R] (STJA0039737)

SKU:
STJA0039737
£150.00 - £540.00
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Rabbit monoclonal anti-Intercellular Adhesion Molecule 1 for use in WB, IHC, IF, IP and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/IP/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :PT0133R
Isotype:IgGk
Conjugation:Unconjugated
Purification:Protein A
Dilution Range:IHC 1:100-200
WB 1:1000-5000
IF 1:200-1000
ELISA 1:5000-20000
IP 1:50-200
Formulation:PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ICAM1
Gene ID:3383
Uniprot ID:ICAM1_HUMAN
Specificity:Endogenous
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Major Group Rhinovirus Receptor
Cd Antigen Cd54
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-877300
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 1 antibody
Anti-Icam-1 antibody
Anti-Major Group Rhinovirus Receptor antibody
Anti-Cd Antigen Cd54 antibody
Anti-ICAM1 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ72888 Anti-ICAM1 antibody (Internal) (STJ72888) Goat Polyclonal Human Pep-ELISA/IF
STJ16102465 Anti-ICAM1 antibody [6F2C3] (STJ16102465) Mouse Monoclonal Human WB/IHC/FC
STJA0005148 Anti-ICAM1 antibody [SM5148] (STJA0005148) Mouse Monoclonal Human IHC/IF
STJ11103840 Anti-ICAM1 antibody (250-480) (STJ11103840) Rabbit Polyclonal Human/Mouse WB/ELISA
STJA0027323 Anti-CD54/ICAM1 antibody [SAA0025] (STJA0027323) Human Monoclonal Human ELISA/FC

Related Products

!