Anti-ICAM-1/CD54 antibody [SRM13063] (STJ11107793)

SKU:
STJ11107793
$163.53 - $719.67
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Rabbit monoclonal Intercellular Adhesion Molecule 1 antibody for use in WB, IHC-P, FC and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/FC/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SRM13063
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB, 1:500-1:2000
IHC-P, 1:50-1:200
FC, 1:50-1:200
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ICAM1
Gene ID:3383
Uniprot ID:ICAM1_HUMAN
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Immunogen Sequence:Human
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
Protein Name Intercellular Adhesion Molecule 1
Icam-1
Major Group Rhinovirus Receptor
Cd Antigen Cd54
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-216083
Reactome: R-HSA-6783783
Reactome: R-HSA-6785807
Reactome: R-HSA-877300
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Intercellular Adhesion Molecule 1 antibody
Anti-Icam-1 antibody
Anti-Major Group Rhinovirus Receptor antibody
Anti-Cd Antigen Cd54 antibody
Anti-ICAM1 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ11108227 Anti-ICAM-1/CD54 antibody [SRM13497] (STJ11108227) Rabbit Monoclonal Rat WB/IHC-P/FC/ELISA
STJ11109067 Anti-ICAM-1/CD54 antibody {APC} (STJ11109067) Rabbit Monoclonal Human FC
STJ11109489 Anti-ICAM-1/CD54 antibody [SRM14759] (STJ11109489) Rabbit Monoclonal Mouse/Rat WB/IF-P/IHC-P/ELISA
STJ11107208 Anti-ICAM-1/CD54 antibody [SRM5305] (STJ11107208) Rabbit Monoclonal Human/Mouse/Rat WB/IHC-P/IF/ICC/ELISA
STJ11104758 Anti-ICAM-1/CD54 antibody [S4758RM] (STJ11104758) Rabbit Monoclonal Mouse/Rat WB/IHC-P/ELISA

Related Products

!