Anti-Human Kappa Light Chain antibody [SRM14670] (STJ11109400)

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STJ11109400
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Host: Rabbit
Applications: WB/IF-P/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14670
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:500-1:1000
IF-P, 1:50-1:200
FC, 1:500-1:1000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IGKCUniprot ID=IGKC_HUMAN"
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Function Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Protein Name Immunoglobulin Kappa Constant
Ig Kappa Chain C Region
Ig Kappa Chain C Region Ag
Ig Kappa Chain C Region Cum
Ig Kappa Chain C Region Eu
Ig Kappa Chain C Region Ou
Ig Kappa Chain C Region Roy
Ig Kappa Chain C Region Ti
Cellular Localisation Secreted
Cell Membrane
Alternative Antibody Names Anti-Immunoglobulin Kappa Constant antibody
Anti-Ig Kappa Chain C Region antibody
Anti-Ig Kappa Chain C Region Ag antibody
Anti-Ig Kappa Chain C Region Cum antibody
Anti-Ig Kappa Chain C Region Eu antibody
Anti-Ig Kappa Chain C Region Ou antibody
Anti-Ig Kappa Chain C Region Roy antibody
Anti-Ig Kappa Chain C Region Ti antibody
Anti-IGKC antibody

Information sourced from Uniprot.org

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