Anti-Human CD70 nanobody [SAA2049] (STJN000564)

Anti-Human CD70 nanobody [SAA2049] (STJN000564)

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STJN000564
€473.13 - €2,040.63
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: ELISA/FC
Reactivity: Human/Cynomolgus
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Cd70 antigen is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA2049
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: CD70
Gene ID: 970
Uniprot ID: CD70_HUMAN
Function Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.
Protein Name Cd70 Antigen
Cd27 Ligand
Cd27-L
Tumor Necrosis Factor Ligand Superfamily Member 7
Cd Antigen Cd70
Database Links Reactome: R-HSA-5669034
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Nanobody Names Anti-Cd70 Antigen nanobody
Anti-Cd27 Ligand nanobody
Anti-Cd27-L nanobody
Anti-Tumor Necrosis Factor Ligand Superfamily Member 7 nanobody
Anti-Cd Antigen Cd70 nanobody
Anti-CD70 nanobody
Anti-CD27L nanobody
Anti-CD27LG nanobody
Anti-TNFSF7 nanobody

Information sourced from Uniprot.org

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