![Anti-Human CD70 nanobody [SAA2049] (STJN000564)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/201177/413275/STJN000564-SDS-PAGE-1__96398.1749232757.jpg?c=1 "Anti-Human CD70 nanobody [SAA2049] (STJN000564)")
![Anti-Human CD70 nanobody [SAA2049] (STJN000564)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/201177/413275/STJN000564-SDS-PAGE-1__96398.1749232757.jpg?c=1 "Anti-Human CD70 nanobody [SAA2049] (STJN000564)")
Anti-Human CD70 nanobody [SAA2049] (STJN000564)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Cd70 antigen is suitable for use in ELISA and Flow Cytometry research applications. |
| Applications | ELISA/FC |
| Host | Alpaca |
| Reactivity | Human/Cynomolgus |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA2049 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CD70 |
| Gene ID | 970 |
| Uniprot ID | CD70_HUMAN |
Additional Info
| Function | Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. |
| Protein Name | Cd70 AntigenCd27 LigandCd27-LTumor Necrosis Factor Ligand Superfamily Member 7Cd Antigen Cd70 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Nanobody Names | Anti-Cd70 Antigen nanobodyAnti-Cd27 Ligand nanobodyAnti-Cd27-L nanobodyAnti-Tumor Necrosis Factor Ligand Superfamily Member 7 nanobodyAnti-Cd Antigen Cd70 nanobodyAnti-CD70 nanobodyAnti-CD27L nanobodyAnti-CD27LG nanobodyAnti-TNFSF7 nanobody |
Information sourced from Uniprot.org