| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Hematopoietic SH2 domain-containing protein (288-338 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HSH2D |
| Gene ID: | 84941 |
| Uniprot ID: | HSH2D_HUMAN |
| Immunogen Region: | 288-338 aa |
| Specificity: | This antibody detects endogenous levels of HSH2D at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human HSH2D at the amino acid range 288-338 |
| Post Translational Modifications | May be phosphorylated by FES and ACK1. |
| Function | May be a modulator of the apoptotic response through its ability to affect mitochondrial stability. Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. |
| Protein Name | Hematopoietic Sh2 Domain-Containing ProteinHematopoietic Sh2 ProteinAdaptor In Lymphocytes Of Unknown Function X |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Hematopoietic Sh2 Domain-Containing Protein antibodyAnti-Hematopoietic Sh2 Protein antibodyAnti-Adaptor In Lymphocytes Of Unknown Function X antibodyAnti-HSH2D antibodyAnti-ALX antibody |
Information sourced from Uniprot.org
