| Function | NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids. |
| Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase Type 617-Beta-Hsd 617-Beta-Hsd6 3-Alpha->Beta-Hydroxysteroid Epimerase3-Alpha->Beta-HseOxidative 3-Alpha Hydroxysteroid DehydrogenaseShort Chain Dehydrogenase/Reductase Family 9c Member 6 |
| Database Links | Reactome: R-HSA-2453902 |
| Cellular Localisation | Microsome MembranePeripheral Membrane ProteinLumenal SideEarly Endosome Membrane |
| Alternative Antibody Names | Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 6 antibodyAnti-17-Beta-Hsd 6 antibodyAnti-17-Beta-Hsd6 antibodyAnti-3-Alpha->Beta-Hydroxysteroid Epimerase antibodyAnti-3-Alpha->Beta-Hse antibodyAnti-Oxidative 3-Alpha Hydroxysteroid Dehydrogenase antibodyAnti-Short Chain Dehydrogenase/Reductase Family 9c Member 6 antibodyAnti-HSD17B6 antibodyAnti-RODH antibodyAnti-SDR9C6 antibody |
Information sourced from Uniprot.org
