• Western blot analysis of lysate from K562, HUVEC cells, using HSD17B4 Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:100
  • Western blot analysis of HuvEc, K562 cells using 17 Beta-HSD4 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-HSD17B4 antibody (41-90 aa) (STJ96751)

SKU:
STJ96751

Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Peroxisomal multifunctional enzyme type 2 (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HSD17B4
Gene ID: 3295
Uniprot ID: DHB4_HUMAN
Immunogen Region: 41-90 aa
Specificity: 17 Beta-HSD4 Polyclonal Antibody detects endogenous levels of 17 Beta-HSD4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human HSD17B4 at the amino acid range 41-90
Function Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway. Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx. Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates.
Protein Name Peroxisomal Multifunctional Enzyme Type 2
Mfe-2
17-Beta-Hydroxysteroid Dehydrogenase 4
17-Beta-Hsd 4
D-Bifunctional Protein
Dbp
Multifunctional Protein 2
Mfp-2
Short Chain Dehydrogenase/Reductase Family 8c Member 1 Cleaved Into -
3r-Hydroxyacyl-Coa Dehydrogenase - Enoyl-Coa Hydratase 2
3-Alpha -7-Alpha -12-Alpha-Trihydroxy-5-Beta-Cholest-24-Enoyl-Coa Hydratase
Database Links Reactome: R-HSA-193368
Reactome: R-HSA-2046106
Reactome: R-HSA-389887
Reactome: R-HSA-390247
Reactome: R-HSA-9033241
Reactome: R-HSA-9033500
Cellular Localisation Peroxisome
Alternative Antibody Names Anti-Peroxisomal Multifunctional Enzyme Type 2 antibody
Anti-Mfe-2 antibody
Anti-17-Beta-Hydroxysteroid Dehydrogenase 4 antibody
Anti-17-Beta-Hsd 4 antibody
Anti-D-Bifunctional Protein antibody
Anti-Dbp antibody
Anti-Multifunctional Protein 2 antibody
Anti-Mfp-2 antibody
Anti-Short Chain Dehydrogenase/Reductase Family 8c Member 1 Cleaved Into - antibody
Anti-3r-Hydroxyacyl-Coa Dehydrogenase - Enoyl-Coa Hydratase 2 antibody
Anti-3-Alpha -7-Alpha -12-Alpha-Trihydroxy-5-Beta-Cholest-24-Enoyl-Coa Hydratase antibody
Anti-HSD17B4 antibody
Anti-EDH17B4 antibody
Anti-SDR8C1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance