Anti-HSD17B11 antibody (71-120 aa) (STJ91378)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DHRS8 at the amino acid range 71-120
General Information
| Short Description | Rabbit polyclonal anti-Estradiol 17-beta-dehydrogenase 11 (71-120 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000IF 1:100-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HSD17B11 |
| Gene ID | 51170 |
| Uniprot ID | DHB11_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DHRS8 at the amino acid range 71-120 |
| Immunogen Region | 71-120 aa |
| Specificity | 17 Beta-HSD11 Polyclonal Antibody detects endogenous levels of 17 Beta-HSD11 protein. |
Additional Info
| Function | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. |
| Protein Name | Estradiol 17-Beta-Dehydrogenase 1117-Beta-Hydroxysteroid Dehydrogenase 1117-Beta-Hsd 1117bhsd1117betahsd1117-Beta-Hydroxysteroid Dehydrogenase Xi17-Beta-Hsd Xi17betahsdxiCutaneous T-Cell Lymphoma-Associated Antigen Hd-Cl-03Ctcl-Associated Antigen Hd-Cl-03Dehydrogenase/Reductase Sdr Family Member 8Retinal Short-Chain Dehydrogenase/Reductase 2Retsdr2Short Chain Dehydrogenase/Reductase Family 16c Member 2 |
| Database Links | Reactome: R-HSA-193144 |
| Cellular Localisation | Endoplasmic ReticulumLipid DropletRedistributed From The Endoplasmic Reticulum To Lipids Droplets In The Cell Upon Induction Of Lipids Droplet Formation |
| Alternative Antibody Names | Anti-Estradiol 17-Beta-Dehydrogenase 11 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase 11 antibodyAnti-17-Beta-Hsd 11 antibodyAnti-17bhsd11 antibodyAnti-17betahsd11 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase Xi antibodyAnti-17-Beta-Hsd Xi antibodyAnti-17betahsdxi antibodyAnti-Cutaneous T-Cell Lymphoma-Associated Antigen Hd-Cl-03 antibodyAnti-Ctcl-Associated Antigen Hd-Cl-03 antibodyAnti-Dehydrogenase/Reductase Sdr Family Member 8 antibodyAnti-Retinal Short-Chain Dehydrogenase/Reductase 2 antibodyAnti-Retsdr2 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 16c Member 2 antibodyAnti-HSD17B11 antibodyAnti-DHRS8 antibodyAnti-PAN1B antibodyAnti-SDR16C2 antibodyAnti-PSEC0029 antibodyAnti-UNQ207 antibodyAnti-PRO233 antibody |
Information sourced from Uniprot.org