| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Estradiol 17-beta-dehydrogenase 11 (71-120 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:5000 IF 1:100-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HSD17B11 |
| Gene ID: | 51170 |
| Uniprot ID: | DHB11_HUMAN |
| Immunogen Region: | 71-120 aa |
| Specificity: | 17 Beta-HSD11 Polyclonal Antibody detects endogenous levels of 17 Beta-HSD11 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DHRS8 at the amino acid range 71-120 |
| Function | Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. |
| Protein Name | Estradiol 17-Beta-Dehydrogenase 11 17-Beta-Hydroxysteroid Dehydrogenase 11 17-Beta-Hsd 11 17bhsd11 17betahsd11 17-Beta-Hydroxysteroid Dehydrogenase Xi 17-Beta-Hsd Xi 17betahsdxi Cutaneous T-Cell Lymphoma-Associated Antigen Hd-Cl-03 Ctcl-Associated Antigen Hd-Cl-03 Dehydrogenase/Reductase Sdr Family Member 8 Retinal Short-Chain Dehydrogenase/Reductase 2 Retsdr2 Short Chain Dehydrogenase/Reductase Family 16c Member 2 |
| Database Links | Reactome: R-HSA-193144 |
| Cellular Localisation | Endoplasmic Reticulum Lipid Droplet Redistributed From The Endoplasmic Reticulum To Lipids Droplets In The Cell Upon Induction Of Lipids Droplet Formation |
| Alternative Antibody Names | Anti-Estradiol 17-Beta-Dehydrogenase 11 antibody Anti-17-Beta-Hydroxysteroid Dehydrogenase 11 antibody Anti-17-Beta-Hsd 11 antibody Anti-17bhsd11 antibody Anti-17betahsd11 antibody Anti-17-Beta-Hydroxysteroid Dehydrogenase Xi antibody Anti-17-Beta-Hsd Xi antibody Anti-17betahsdxi antibody Anti-Cutaneous T-Cell Lymphoma-Associated Antigen Hd-Cl-03 antibody Anti-Ctcl-Associated Antigen Hd-Cl-03 antibody Anti-Dehydrogenase/Reductase Sdr Family Member 8 antibody Anti-Retinal Short-Chain Dehydrogenase/Reductase 2 antibody Anti-Retsdr2 antibody Anti-Short Chain Dehydrogenase/Reductase Family 16c Member 2 antibody Anti-HSD17B11 antibody Anti-DHRS8 antibody Anti-PAN1B antibody Anti-SDR16C2 antibody Anti-PSEC0029 antibody Anti-UNQ207 antibody Anti-PRO233 antibody |
Information sourced from Uniprot.org