Anti-HS3ST1 antibody (201-251 aa) (STJ197590)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human HS3S1 at the amino acid range 201-251
General Information
| Short Description | Rabbit polyclonal anti-Heparan sulfate glucosamine 3-O-sulfotransferase 1 (201-251 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HS3ST1 |
| Gene ID | 9957 |
| Uniprot ID | HS3S1_HUMAN |
| Immunogen | Synthesized peptide derived from the human HS3S1 at the amino acid range 201-251 |
| Immunogen Region | 201-251 aa |
| Specificity | This antibody detects endogenous levels of human HS3S1 |
Additional Info
| Function | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. |
| Protein Name | Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 13-Ost-1Heparan Sulfate 3-O-Sulfotransferase 1H3-Ost-1 |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus Lumen |
| Alternative Antibody Names | Anti-Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1 antibodyAnti-Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 1 antibodyAnti-3-Ost-1 antibodyAnti-Heparan Sulfate 3-O-Sulfotransferase 1 antibodyAnti-H3-Ost-1 antibodyAnti-HS3ST1 antibodyAnti-3OST antibodyAnti-3OST1 antibody |
Information sourced from Uniprot.org