| Function | Catalyzes the transfer of a sulfo group from 3'-phospho-5'-adenylyl sulfate (PAPS) to the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within the heparan sulfate (HS) chain and participates in HS biosynthesis. Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme. |
| Protein Name | Heparan Sulfate 2-O-Sulfotransferase 12-O-Sulfotransferase2-Ost2ostHs 2-O-SulfotransferaseHeparan Sulfate 2-Sulfotransferase |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Heparan Sulfate 2-O-Sulfotransferase 1 antibodyAnti-2-O-Sulfotransferase antibodyAnti-2-Ost antibodyAnti-2ost antibodyAnti-Hs 2-O-Sulfotransferase antibodyAnti-Heparan Sulfate 2-Sulfotransferase antibodyAnti-HS2ST1 antibodyAnti-HS2ST antibodyAnti-KIAA0448 antibody |
Information sourced from Uniprot.org