• Western blot analysis of various lysates using HS2ST1 Rabbit polyclonal antibody (STJ115778) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-HS2ST1 antibody (1-229) (STJ115778)

SKU:
STJ115778

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HS2ST1 (1-229) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HS2ST1
Gene ID: 9653
Uniprot ID: HS2ST_HUMAN
Immunogen Region: 1-229
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-229 of human HS2ST1 (NP_001127964.1).
Immunogen Sequence: MGLLRIMMPPKLQLLAVVAF AVAMLFLENQIQKLEESRSK LERAIARHEVREIEQRHTMD GPRQDATLDEEEDMVIIYNR VPKTASTSFTNIAYDLCAKN KYHVLHINTTKNNPVMSLQD QVRFVKNITSWKEMKPGFYH GHVSYLDFAKFGVKKKPIYI NVIRDPIERLVSYYYFLRFG DDYRPGLRRRKQGDKKTFDE CVAEGGSDCAPEKLWLQIPF FCGHSSECW
Post Translational Modifications N-glycosylated.
Function Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues.
Protein Name Heparan Sulfate 2-O-Sulfotransferase 1
2-O-Sulfotransferase
2ost
Database Links Reactome: R-HSA-2022928
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Heparan Sulfate 2-O-Sulfotransferase 1 antibody
Anti-2-O-Sulfotransferase antibody
Anti-2ost antibody
Anti-HS2ST1 antibody
Anti-HS2ST antibody
Anti-KIAA0448 antibody

Information sourced from Uniprot.org

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