| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HRNR (1-200) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HRNR |
| Gene ID: |
388697 |
| Uniprot ID: |
HORN_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HRNR (NP_001009931.1). |
| Immunogen Sequence: |
MPKLLQGVITVIDVFYQYAT QHGEYDTLNKAELKELLENE FHQILKNPNDPDTVDIILQS LDRDHNKKVDFTEYLLMIFK LVQARNKIIGKDYCQVSGSK LRDDTHQHQEEQEETEKEEN KRQESSFSHSSWSAGENDSY SRNVRGSLKPGTESISRRLS FQRDFSGQHNSYSGQSSSYG EQNSDSHQSSGRGQCGSGSG |
| Tissue Specificity | Expressed in cornified epidermis, psoriatic and regenerating skin after wounding. Found in the upper granular layer and in the entire cornified layer of epidermis. |
| Post Translational Modifications | Processed during the process of epidermal differentiation. Forms covalent cross-links mediated by transglutaminase TGM3, between glutamine and the epsilon-amino group of lysine residues (in vitro). |
| Function | Component of the epidermal cornified cell envelopes. |
| Protein Name | Hornerin |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleFound In Keratohyalin Granules In The Granular Cells Of The Epidermis |
| Alternative Antibody Names | Anti-Hornerin antibodyAnti-HRNR antibodyAnti-S100A18 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
