| Host: | Rabbit |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HRNR |
| Gene ID: | 388697 |
| Uniprot ID: | HORN_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HRNR (NP_001009931.1). |
| Immunogen Sequence: | MPKLLQGVITVIDVFYQYAT QHGEYDTLNKAELKELLENE FHQILKNPNDPDTVDIILQS LDRDHNKKVDFTEYLLMIFK LVQARNKIIGKDYCQVSGSK LRDDTHQHQEEQEETEKEEN KRQESSFSHSSWSAGENDSY SRNVRGSLKPGTESISRRLS FQRDFSGQHNSYSGQSSSYG EQNSDSHQSSGRGQCGSGSG |
| Tissue Specificity | Expressed in cornified epidermis, psoriatic and regenerating skin after wounding. Found in the upper granular layer and in the entire cornified layer of epidermis. |
| Post Translational Modifications | Processed during the process of epidermal differentiation. Forms covalent cross-links mediated by transglutaminase TGM3, between glutamine and the epsilon-amino group of lysine residues (in vitro). |
| Function | Component of the epidermal cornified cell envelopes. |
| Protein Name | Hornerin |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleFound In Keratohyalin Granules In The Granular Cells Of The Epidermis |
| Alternative Antibody Names | Anti-Hornerin antibodyAnti-HRNR antibodyAnti-S100A18 antibody |
Information sourced from Uniprot.org