Anti-HRH4 antibody (194-304) (STJ112190)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HRH4 (194-304) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HRH4 |
| Gene ID | 59340 |
| Uniprot ID | HRH4_HUMAN |
| Immunogen Region | 194-304 |
| Immunogen Sequence | NMNIYWSLWKRDHLSRCQSH PGLTAVSSNICGHSFRGRLS SRRSLSASTEVPASFHSERQ RRKSSLMFSSRTKMNSNTIA SKMGSFSQSDSVALHQREHV ELLRARRLAKS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 194-304 of human HRH4 (NP_067637.2). |
Additional Info
| Tissue Specificity | Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, including the heart, kidney, liver, lung, pancreas, skeletal muscle, prostate, small intestine, spleen, testis, colon, fetal liver and lymph node. |
| Function | The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). |
| Protein Name | Histamine H4 ReceptorH4rHh4rAxor35G-Protein Coupled Receptor 105Gprv53Pfi-013Sp9144 |
| Database Links | Reactome: R-HSA-390650Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Histamine H4 Receptor antibodyAnti-H4r antibodyAnti-Hh4r antibodyAnti-Axor35 antibodyAnti-G-Protein Coupled Receptor 105 antibodyAnti-Gprv53 antibodyAnti-Pfi-013 antibodyAnti-Sp9144 antibodyAnti-HRH4 antibodyAnti-GPCR105 antibody |
Information sourced from Uniprot.org