| Short Description : | Rabbit polyclonal HRH2 (150-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HRH2 |
| Gene ID: | 3274 |
| Uniprot ID: | HRH2_HUMAN |
| Immunogen Region: | 150-250 |
| Immunogen Sequence: | SFLSIHLGWNSRNETSKGNH TTSKCKVQVNEVYGLVDGLV TFYLPLLIMCITYYRIFKVA RDQAKRINHISSWKAATIRE HKATVTLAAVMGAFIICWFP Y |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HRH2 (NP_001124527.1). |
| Function | The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway. |
| Protein Name | Histamine H2 ReceptorH2rHh2rGastric Receptor I |
| Database Links | Reactome: R-HSA-390650Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Histamine H2 Receptor antibodyAnti-H2r antibodyAnti-Hh2r antibodyAnti-Gastric Receptor I antibodyAnti-HRH2 antibody |
Information sourced from Uniprot.org
