Anti-HPV antibody [CAMVR-1&C1P5] (STJ180457)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak+ IgG1k
ImmunogenHuman papilloma virus type 16 major capsid protein L1 and recombinant full-length protein corresponding to HPV16 E6 + HPV18 E6
General Information
| Short Description | Mouse monoclonal HPV antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | CAMVR-1&C1P5 |
| Isotype | IgG2ak+ IgG1k |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:100-200 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Target Information
| Immunogen | Human papilloma virus type 16 major capsid protein L1 and recombinant full-length protein corresponding to HPV16 E6 + HPV18 E6 |
| Specificity | Positive control: HPV infected cells or tissue |
Additional Info
| Background | Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high-risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high-risk types. Mutational analysis has shown that the E6 and E7 genes of the high-risk HPVs are necessary and sufficient for HPV transforming function. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16,-18 or-33. |
Information sourced from Uniprot.org