Human cervical carcinoma stained with anti-HPV antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear and cytoplasmic staining of carcinoma cells.

Anti-HPV antibody [CAMVR-1&C1P5] (STJ180457)

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STJ180457
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-HPV is suitable for use in Immunohistochemistry research applications.
Clonality : Monoclonal
Clone ID : CAMVR-1&C1P5
Conjugation: Unconjugated
Isotype: IgG2a/Kappa + IgG1/Kappa
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Specificity: Positive control: HPV infected cells or tissue
Immunogen: Human papilloma virus type 16 major capsid protein L1 and recombinant full-length protein corresponding to HPV16 E6 + HPV18 E6
Background Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high-risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high-risk types. Mutational analysis has shown that the E6 and E7 genes of the high-risk HPVs are necessary and sufficient for HPV transforming function. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16,-18 or-33.

Information sourced from Uniprot.org

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