| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-HPV is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | CAMVR-1&C1P5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a/Kappa + IgG1/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Specificity: | Positive control: HPV infected cells or tissue |
| Immunogen: | Human papilloma virus type 16 major capsid protein L1 and recombinant full-length protein corresponding to HPV16 E6 + HPV18 E6 |
| Background | Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high-risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high-risk types. Mutational analysis has shown that the E6 and E7 genes of the high-risk HPVs are necessary and sufficient for HPV transforming function. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16,-18 or-33. |
Information sourced from Uniprot.org