| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BLOC-2 complex member HPS6 (168-218 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HPS6 |
| Gene ID: |
79803 |
| Uniprot ID: |
HPS6_HUMAN |
| Immunogen Region: |
168-218 aa |
| Specificity: |
This antibody detects endogenous levels of HPS6 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human HPS6 at the amino acid range 168-218 |
| Function | May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning. |
| Protein Name | Bloc-2 Complex Member Hps6Hermansky-Pudlak Syndrome 6 ProteinRuby-Eye Protein HomologRu |
| Cellular Localisation | Microsome MembraneCytoplasmCytosolEarly Endosome MembraneLysosome Membrane |
| Alternative Antibody Names | Anti-Bloc-2 Complex Member Hps6 antibodyAnti-Hermansky-Pudlak Syndrome 6 Protein antibodyAnti-Ruby-Eye Protein Homolog antibodyAnti-Ru antibodyAnti-HPS6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
