Anti-HPS4 antibody (387-708) (STJ118597)

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STJ118597
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HPS4
Gene ID: 89781
Uniprot ID: HPS4_HUMAN
Immunogen Region: 387-708
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 387-708 of human HPS4 (NP_071364.4).
Immunogen Sequence: FAFLHVPVPDGRAPYCKASL SASSSLEPTPPEDTAISSLR PPSAPEMLTQHGAQEQLEDH PGHSSQAPIPRADPLPRRTR RPLLLPRLDPGQRGNKLPTG EQGLDEDVDGVCESHAAPGL ECSSGSANCQGAGPSADGIS SRLTPAESCMGLVRMNLYTH CVKGLVLSLLAEEPLLGDSA AIEEVYHSSLASLNGLEVHL KETLPRDEAASTSSTYNFTH YDRIQSLLMANLPQVATPQ
Function Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.
Protein Name Bloc-3 Complex Member Hps4
Hermansky-Pudlak Syndrome 4 Protein
Light-Ear Protein Homolog
Database Links Reactome: R-HSA-8876198
Alternative Antibody Names Anti-Bloc-3 Complex Member Hps4 antibody
Anti-Hermansky-Pudlak Syndrome 4 Protein antibody
Anti-Light-Ear Protein Homolog antibody
Anti-HPS4 antibody
Anti-KIAA1667 antibody

Information sourced from Uniprot.org