• Immunofluorescence analysis of L929 cells using HPS4 Rabbit polyclonal antibody (STJ118597) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of C6 cells using HPS4 Rabbit polyclonal antibody (STJ118597) at dilution of 1:100. Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
  • Western blot analysis of lysates from U-87MG cells, using HPS4 Rabbit polyclonal antibody (STJ118597) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-HPS4 antibody (387-708) (STJ118597)

SKU:
STJ118597

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HPS4 (387-708) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HPS4
Gene ID: 89781
Uniprot ID: HPS4_HUMAN
Immunogen Region: 387-708
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 387-708 of human HPS4 (NP_071364.4).
Immunogen Sequence: FAFLHVPVPDGRAPYCKASL SASSSLEPTPPEDTAISSLR PPSAPEMLTQHGAQEQLEDH PGHSSQAPIPRADPLPRRTR RPLLLPRLDPGQRGNKLPTG EQGLDEDVDGVCESHAAPGL ECSSGSANCQGAGPSADGIS SRLTPAESCMGLVRMNLYTH CVKGLVLSLLAEEPLLGDSA AIEEVYHSSLASLNGLEVHL KETLPRDEAASTSSTYNFTH YDRIQSLLMANLPQVATPQ
Function Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.
Protein Name Bloc-3 Complex Member Hps4
Hermansky-Pudlak Syndrome 4 Protein
Light-Ear Protein Homolog
Database Links Reactome: R-HSA-8876198
Alternative Antibody Names Anti-Bloc-3 Complex Member Hps4 antibody
Anti-Hermansky-Pudlak Syndrome 4 Protein antibody
Anti-Light-Ear Protein Homolog antibody
Anti-HPS4 antibody
Anti-KIAA1667 antibody

Information sourced from Uniprot.org

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