| Short Description : | Mouse monoclonal anti-BLOC-3 complex member HPS1 for use in WB and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 5G12G2 |
| Isotype: | IgG2a |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HPS1 |
| Gene ID: | 3257 |
| Uniprot ID: | HPS1_HUMAN |
| Immunogen: | Purified recombinant fragment of HPS-1 expressed in E. Coli. |
| Specificity: | HPS-1 Monoclonal Antibody detects endogenous levels of HPS-1 protein. |
| Function | Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38. |
| Protein Name | Bloc-3 Complex Member Hps1Hermansky-Pudlak Syndrome 1 Protein |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Bloc-3 Complex Member Hps1 antibodyAnti-Hermansky-Pudlak Syndrome 1 Protein antibodyAnti-HPS1 antibodyAnti-HPS antibody |
Information sourced from Uniprot.org
