Host: |
Mouse |
Applications: |
WB/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-BLOC-3 complex member HPS1 is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Monoclonal |
Clone ID: |
5G12G2 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2a |
Formulation: |
Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
HPS1 |
Gene ID: |
3257 |
Uniprot ID: |
HPS1_HUMAN |
Specificity: |
HPS-1 Monoclonal Antibody detects endogenous levels of HPS-1 protein. |
Immunogen: |
Purified recombinant fragment of HPS-1 expressed in E. Coli. |
Function | Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38. |
Protein Name | Bloc-3 Complex Member Hps1Hermansky-Pudlak Syndrome 1 Protein |
Database Links | Reactome: R-HSA-8876198 |
Alternative Antibody Names | Anti-Bloc-3 Complex Member Hps1 antibodyAnti-Hermansky-Pudlak Syndrome 1 Protein antibodyAnti-HPS1 antibodyAnti-HPS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance