Anti-HNRNPH1 antibody (191-449) (STJ27720)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HNRNPH1 (191-449) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HNRNPH1 |
| Gene ID | 3187 |
| Uniprot ID | HNRH1_HUMAN |
| Immunogen Region | 191-449 |
| Immunogen Sequence | VRTHYDPPRKLMAMQRPGPY DRPGAGRGYNSIGRGAGFER MRRGAYGGGYGGYDDYNGYN DGYGFGSDRFGRDLNYCFSG MSDHRYGDGGSTFQSTTGHC VHMRGLPYRATENDIYNFFS PLNPVRVHIEIGPDGRVTGE ADVEFATHEDAVAAMSKDKA NMQHRYVELFLNSTAGASGG AYEHRYVELFLNSTAGASGG AYGSQMMGGMGLSNQSSYGG PASQQLSGGYGGGYGGQSS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 191-449 of human HNRNPH1 (NP_005511.1). |
Additional Info
| Tissue Specificity | Expressed ubiquitously. |
| Function | This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein HHnrnp H Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein H - N-Terminally Processed |
| Database Links | Reactome: R-HSA-6803529Reactome: R-HSA-72163Reactome: R-HSA-72203 |
| Cellular Localisation | NucleusNucleoplasm |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein H antibodyAnti-Hnrnp H Cleaved Into - Heterogeneous Nuclear Ribonucleoprotein H - N-Terminally Processed antibodyAnti-HNRNPH1 antibodyAnti-HNRPH antibodyAnti-HNRPH1 antibody |
Information sourced from Uniprot.org