Anti-HNRNPAB antibody (1-285) (STJ119592)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal HNRantibody (1-285) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HNRNPAB |
| Gene ID | 3182 |
| Uniprot ID | ROAA_HUMAN |
| Immunogen Region | 1-285 |
| Immunogen Sequence | MSEAGEEQPMETTGATENGH EAVPEGESPAGAGTGAAAGA GGATAAPPSGNQNGAEGDQI NASKNEEDAGKMFVGGLSWD TSKKDLKDYFTKFGEVVDCT IKMDPNTGRSRGFGFILFKD AASVEKVLDQKEHRLDGRVI DPKKAMAMKKDPVKKIFVGG LNPEATEEKIREYFGEFGEI EAIELPMDPKLNKRRGFVFI TFKEEEPVKKVLEKKFHTVS GSKCEIKVAQPKEVYQQQQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human HNRPAB (NP_004490.2). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Dimethylation at Arg-322 is probably asymmetric. |
| Function | Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site. |
| Protein Name | Heterogeneous Nuclear Ribonucleoprotein A/BHnrnp A/BApobec1-Binding Protein 1Abbp-1 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmLocalized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas |
| Alternative Antibody Names | Anti-Heterogeneous Nuclear Ribonucleoprotein A/B antibodyAnti-Hnrnp A/B antibodyAnti-Apobec1-Binding Protein 1 antibodyAnti-Abbp-1 antibodyAnti-HNRNPAB antibodyAnti-ABBP1 antibodyAnti-HNRPAB antibody |
Information sourced from Uniprot.org