| Short Description : | Rabbit polyclonal HNMT (1-292) antibody for use in WB, IP and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IP/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IP:0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HNMT |
| Gene ID: | 3176 |
| Uniprot ID: | HNMT_HUMAN |
| Immunogen Region: | 1-292 |
| Immunogen Sequence: | MASSMRSLFSDHGKYVESFR RFLNHSTEHQCMQEFMDKKL PGIIGRIGDTKSEIKILSIG GGAGEIDLQILSKVQAQYPG VCINNEVVEPSAEQIAKYKE LVAKTSNLENVKFAWHKETS SEYQSRMLEKKELQKWDFIH MIQMLYYVKDIPATLKFFHS LLGTNAKMLIIVVSGSSGWD KLWKKYGSRFPQDDLCQYIT SDDLTQMLDNLGLKYECYDL LSTMDISDCFIDGNENGDL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-292 of human HNMT (NP_008826.1). |
| Function | Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. |
| Protein Name | Histamine N-MethyltransferaseHmt |
| Database Links | Reactome: R-HSA-2408508Reactome: R-HSA-70921 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Histamine N-Methyltransferase antibodyAnti-Hmt antibodyAnti-HNMT antibody |
Information sourced from Uniprot.org
