Anti-HNF1A antibody (STJ193036)

SKU:
STJ193036
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Hepatocyte nuclear factor 1-alpha is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HNF1A
Gene ID: 6927
Uniprot ID: HNF1A_HUMAN
Specificity: HNF1A Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Post Translational Modifications Ubiquitinated in s SPOP-dependent manner.leading to prteasomal degradation.
Function Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Activates the transcription of CYP1A2, CYP2E1 and CYP3A11. (Microbial infection) Plays a crucial role for hepatitis B virus gene transcription and DNA replication. Mechanistically, synergistically cooperates with NR5A2 to up-regulate the activity of one of the critical cis-elements in the hepatitis B virus genome enhancer II (ENII).
Protein Name Hepatocyte Nuclear Factor 1-Alpha
Hnf-1-Alpha
Hnf-1a
Liver-Specific Transcription Factor Lf-B1
Lfb1
Transcription Factor 1
Tcf-1
Database Links Reactome: R-HSA-210745
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Hepatocyte Nuclear Factor 1-Alpha antibody
Anti-Hnf-1-Alpha antibody
Anti-Hnf-1a antibody
Anti-Liver-Specific Transcription Factor Lf-B1 antibody
Anti-Lfb1 antibody
Anti-Transcription Factor 1 antibody
Anti-Tcf-1 antibody
Anti-HNF1A antibody
Anti-TCF1 antibody

Information sourced from Uniprot.org

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