• Western blot analysis of various lysates using HMOX2 Rabbit polyclonal antibody (STJ24054) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-HMOX2 antibody (1-270) (STJ24054)

SKU:
STJ24054

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HMOX2
Gene ID: 3163
Uniprot ID: HMOX2_HUMAN
Immunogen Region: 1-270
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HMOX2 (NP_002125.3).
Immunogen Sequence: MSAEVETSEGVDESEKKNSG ALEKENQMRMADLSELLKEG TKEAHDRAENTQFVKDFLKG NIKKELFKLATTALYFTYSA LEEEMERNKDHPAFAPLYFP MELHRKEALTKDMEYFFGEN WEEQVQCPKAAQKYVERIHY IGQNEPELLVAHAYTRYMGD LSGGQVLKKVAQRALKLPST GEGTQFYLFENVDNAQQFKQ LYRARMNALDLNMKTKERIV EEANKAFEYNMQIFNELDQ
Post Translational Modifications A soluble form arises by proteolytic removal of the membrane anchor. S-nitrosylated by BLVRB.
Function Heme oxygenase 2: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Heme oxygenase 2 soluble form: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.
Protein Name Heme Oxygenase 2
Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-6798695
Reactome: R-HSA-8980692
Reactome: R-HSA-917937
Reactome: R-HSA-9707564
Cellular Localisation Microsome Membrane
Single-Pass Type Iv Membrane Protein
Cytoplasmic Side
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Heme Oxygenase 2 antibody
Anti-Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form antibody
Anti-HMOX2 antibody
Anti-HO2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance