• Western blot analysis of 3T3 Cell lysate using HO-1 mouse Monoclonal monoclonal antibody diluted at 1:2,000.
  • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-HMOX1 antibody [Mix] (STJ196663)

SKU:
STJ196663

£168.00 - £226.00
Current Stock:
Host: Mouse
Applications: IHC/WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Heme oxygenase 1 is suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: Mix
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IF 1:50-200
IHC-P 1:50-200
WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HMOX1
Gene ID: 3162
Uniprot ID: HMOX1_HUMAN
Specificity: This antibody detects endogenous levels of HO-1 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from the human HO-1
Post Translational Modifications A soluble form arises by proteolytic removal of the membrane anchor.
Function Heme oxygenase 1: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis. Heme oxygenase 1: (Microbial infection) During SARS-COV-2 infection, promotes SARS-CoV-2 ORF3A-mediated autophagy but is unlikely to be required for ORF3A-mediated induction of reticulophagy. Heme oxygenase 1 soluble form: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.
Protein Name Heme Oxygenase 1
Ho-1 Cleaved Into - Heme Oxygenase 1 Soluble Form
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-6785807
Reactome: R-HSA-844456
Reactome: R-HSA-917937
Reactome: R-HSA-9609523
Reactome: R-HSA-9660826
Reactome: R-HSA-9707564
Reactome: R-HSA-9707587
Reactome: R-HSA-9707616
Reactome: R-HSA-9818027
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Iv Membrane Protein
Cytoplasmic Side
Alternative Antibody Names Anti-Heme Oxygenase 1 antibody
Anti-Ho-1 Cleaved Into - Heme Oxygenase 1 Soluble Form antibody
Anti-HMOX1 antibody
Anti-HO antibody
Anti-HO1 antibody

Information sourced from Uniprot.org

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