Host: |
Goat |
Applications: |
Pep-ELISA/WB |
Reactivity: |
Human/Dog |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-HMGI-C/HMGA2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
ELISA-antibody detection limit dilution 1:8000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
HMGA2 |
Gene ID: |
8091 |
Uniprot ID: |
HMGA2_HUMAN |
Immunogen Region: |
Internal |
Accession Number: |
NP_003474.1; NP_003475.1 |
Specificity: |
This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1. |
Immunogen Sequence: |
KAAQKKAEATGEK |
Function | Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner. |
Protein Name | High Mobility Group Protein Hmgi-CHigh Mobility Group At-Hook Protein 2 |
Database Links | Reactome: R-HSA-2559584 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-High Mobility Group Protein Hmgi-C antibodyAnti-High Mobility Group At-Hook Protein 2 antibodyAnti-HMGA2 antibodyAnti-HMGIC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance