Anti-HMGA2 antibody [SRM14744] (STJ11109474)

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STJ11109474
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Host: Rabbit
Applications: WB/IHC-P/IF/ICC/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : SRM14744
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity purification
Dilution Range: WB, 1:2000-1:8000
IHC-P, 1:200-1:2000
IF/ICC, 1:200-1:800
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HMGA2
Gene ID: 8091
Uniprot ID: HMGA2_HUMAN
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Post Translational Modifications Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2.
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner.
Protein Name High Mobility Group Protein Hmgi-C
High Mobility Group At-Hook Protein 2
Database Links Reactome: R-HSA-2559584
Cellular Localisation Nucleus
Alternative Antibody Names Anti-High Mobility Group Protein Hmgi-C antibody
Anti-High Mobility Group At-Hook Protein 2 antibody
Anti-HMGA2 antibody
Anti-HMGIC antibody

Information sourced from Uniprot.org

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