Anti-HMGA2 antibody [IHC492] (STJA0042189)

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STJA0042189
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Short Description :Rabbit monoclonal anti-HMGA2 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-p
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :IHC492
Conjugation:Unconjugated
Formulation:Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol:HMGA2
Gene ID:8091
Uniprot ID:HMGA2_HUMAN
Specificity:Tested and validated on lung carcinoma tissue.
Post Translational Modifications Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2.
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner.
Protein Name High Mobility Group Protein Hmgi-C
High Mobility Group At-Hook Protein 2
Database Links Reactome: R-HSA-2559584
Cellular Localisation Nucleus
Alternative Antibody Names Anti-High Mobility Group Protein Hmgi-C antibody
Anti-High Mobility Group At-Hook Protein 2 antibody
Anti-HMGA2 antibody
Anti-HMGIC antibody

Information sourced from Uniprot.org

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