| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-High mobility group protein 20A (208-258) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HMG20A |
| Gene ID: | 10363 |
| Uniprot ID: | HM20A_HUMAN |
| Immunogen Region: | 208-258 |
| Specificity: | This antibody detects endogenous levels of human HM20A |
| Immunogen: | Synthesized peptide derived from human HM20A AA range: 208-258 |
| Function | Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4. |
| Protein Name | High Mobility Group Protein 20aHmg Box-Containing Protein 20aHmg Domain-Containing Protein 1Hmg Domain-Containing Protein Hmgx1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-High Mobility Group Protein 20a antibodyAnti-Hmg Box-Containing Protein 20a antibodyAnti-Hmg Domain-Containing Protein 1 antibodyAnti-Hmg Domain-Containing Protein Hmgx1 antibodyAnti-HMG20A antibodyAnti-HMGX1 antibodyAnti-HMGXB1 antibody |
Information sourced from Uniprot.org