| Background | HMB-45 is specific for an antigen present in immature melanosomes, cutaneous melanocytes, and prenatal and infantile retinal pigment epithelium cells. It is therefore effective for identifying malignant melanoma, and differentiating metastatic amelanotic melanoma from a number on conditions where the discrimination is often extremely difficult, including large cell lymphomas, sarcomas, spindle cell carcinomas, and various types on mesenchymal neoplasms. This antibody can also differentiate between junctional nevus and intradermal nevus cells, and between fetal or neonatal melanocytes and normal adult melanocytes. |
Information sourced from Uniprot.org
![Anti-Melanoma antibody [HMB-45] (STJ16100391)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/149108/346729/STJ16100391_1__65580.1681998819.jpg?c=1 "Anti-Melanoma antibody [HMB-45] (STJ16100391)")
