| Host: |
Rabbit |
| Applications: |
WB/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Hydroxycarboxylic acid receptor 3 and Hydroxycarboxylic acid receptor 2 (285-334 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HCAR3HCAR2 |
| Gene ID: |
8843338442 |
| Uniprot ID: |
HCAR3_HUMANHCAR2_HUMAN |
| Immunogen Region: |
285-334 aa |
| Specificity: |
HM74 Polyclonal Antibody detects endogenous levels of HM74 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human GPR109 at the amino acid range 285-334 |
| Function | Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. |
| Protein Name | Hydroxycarboxylic Acid Receptor 3G-Protein Coupled Receptor 109bG-Protein Coupled Receptor Hm74G-Protein Coupled Receptor Hm74bNiacin Receptor 2Nicotinic Acid Receptor 2 |
| Database Links | Reactome: R-HSA-3296197Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Hydroxycarboxylic Acid Receptor 3 antibodyAnti-G-Protein Coupled Receptor 109b antibodyAnti-G-Protein Coupled Receptor Hm74 antibodyAnti-G-Protein Coupled Receptor Hm74b antibodyAnti-Niacin Receptor 2 antibodyAnti-Nicotinic Acid Receptor 2 antibodyAnti-HCAR3 antibodyAnti-GPR109B antibodyAnti-HCA3 antibodyAnti-HM74B antibodyAnti-NIACR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
