• Immunohistochemistry analysis of paraffin-embedded esophagus cancer tissues (left) and human lung cancer (right) with DAB staining using HXK II monoclonal antibody.
  • Flow cytometric analysis of K562 cells using HXK II monoclonal antibody (green) and negative control (purple).
  • Western blot analysis using HXK II monoclonal antibody against Jurkat (1) , HeLa (2) and HEK293 (3) cell lysate.

Anti-HK2 antibody [3D3] (STJ98152)

SKU:
STJ98152

£139.00 - £336.00
Current Stock:
Host: Mouse
Applications: WB/IHC/IF/FC/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Hexokinase-2 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry and ELISA research applications.
Clonality: Monoclonal
Clone ID: 3D3
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
FC 1:200-1:400
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HK2
Gene ID: 3099
Uniprot ID: HXK2_HUMAN
Specificity: HXK II Monoclonal Antibody detects endogenous levels of HXK II protein.
Immunogen: Purified recombinant fragment of human HXK II expressed in E. Coli.
Function Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis.
Protein Name Hexokinase-2
Hexokinase Type Ii
Hk Ii
Hexokinase-B
Muscle Form Hexokinase
Database Links Reactome: R-HSA-70171
Cellular Localisation Mitochondrion Outer Membrane
Peripheral Membrane Protein
Cytoplasm
Cytosol
The Mitochondrial-Binding Peptide (Mbp) Region Promotes Association With The Mitochondrial Outer Membrane
The Interaction With The Mitochondrial Outer Membrane Via The Mitochondrial-Binding Peptide (Mbp) Region Promotes Higher Stability Of The Protein
Release From The Mitochondrial Outer Membrane Into The Cytosol Induces Permeability Transition Pore (Ptp) Opening And Apoptosis
Alternative Antibody Names Anti-Hexokinase-2 antibody
Anti-Hexokinase Type Ii antibody
Anti-Hk Ii antibody
Anti-Hexokinase-B antibody
Anti-Muscle Form Hexokinase antibody
Anti-HK2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance