| Short Description : | Rabbit polyclonal antibody anti-Histone H3 (1-50) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Applications: | ELISA/IHC/IP/WB |
| Host: | Rabbit |
| Reactivity: | Human/Monkey/S.cerevisiae |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Biotin |
| Concentration: | 0.55-0.75 µg/µl |
| Purification: | Affinity Purified |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:150IHC: 1:100 |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Immunogen: | Synthetic peptide taken within amino acid 1-50 on Sacchoromyces cerevisiae protein HH3 protein. |
| Immunogen Region: | 1-50 |
| Background | Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Can bind to DNA (in vitro). |
Information sourced from Uniprot.org
