| Short Description : | Rabbit polyclonal anti-Huntingtin-interacting protein 1-related protein (554-604 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HIP1R |
| Gene ID: | 9026 |
| Uniprot ID: | HIP1R_HUMAN |
| Immunogen: | Synthesized peptide derived from the human HIP1R at the amino acid range 554-604 |
| Immunogen Region: | 554-604 aa |
| Specificity: | This antibody detects endogenous levels of HIP1R at Human/Mouse |
| Function | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. |
| Protein Name | Huntingtin-Interacting Protein 1-Related ProteinHip1-Related ProteinHuntingtin-Interacting Protein 12Hip-12 |
| Database Links | Reactome: R-HSA-432722Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndomembrane SystemCytoplasmic VesicleClathrin-Coated Vesicle MembraneMembrane-Associated ProteinMainly Localized At The Endocytic Compartments And In The Perinuclear Region |
| Alternative Antibody Names | Anti-Huntingtin-Interacting Protein 1-Related Protein antibodyAnti-Hip1-Related Protein antibodyAnti-Huntingtin-Interacting Protein 12 antibodyAnti-Hip-12 antibodyAnti-HIP1R antibodyAnti-HIP12 antibodyAnti-KIAA0655 antibody |
Information sourced from Uniprot.org
